Who manages day-to-day trial operations?

Who manages day-to-day trial operations?

• A. CRC
• B. PI
• C. Sponsor
• D. IRB

Answer: (A)

Managing day-to-day trial operations means handling the ongoing, on-site tasks required to run the study—like coordinating visits, obtaining informed consent, collecting data, keeping regulatory documents up to date, and ensuring procedures follow the protocol. This responsibility falls to the Clinical Research Coordinator, who handles these operational details under the supervision of the Principal Investigator. The PI is ultimately accountable for the study’s safety and scientific integrity but delegates routine management, the sponsor provides the protocol and oversight, and the IRB focuses on ethics and participant protections rather than daily site activities.

Managing day-to-day trial operations means handling the ongoing, on-site tasks required to run the study—like coordinating visits, obtaining informed consent, collecting data, keeping regulatory documents up to date, and ensuring procedures follow the protocol. This responsibility falls to the Clinical Research Coordinator, who handles these operational details under the supervision of the Principal Investigator. The PI is ultimately accountable for the study’s safety and scientific integrity but delegates routine management, the sponsor provides the protocol and oversight, and the IRB focuses on ethics and participant protections rather than daily site activities.